ACARBOSE – Drug Information

Generic Name: Acarbose

Therapeutic Classification: Alpha-glucosidase inhibitor

Drug information about Acarbose. Learn its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name of the drug and its price list. In 1991, aceclofenac was developed as an analog of a commonly prescribed NSAID, Diclofenac, via chemical modification in effort to improve the gastrointestinal tolerability of the drug.

Mechanism of Action:

It inhibits enzymes (glycoside hydrolases) which needed to break down carbohydrates to release glucose, which is subsequently absorbed in the blood. Specifically, alpha-glucosidase enzymes in the small intestines, and pancreatic alpha-amylase. Inhibition of these enzyme systems reduces the rate of digestion of carbohydrates. Thus resulting less glucose is absorbed in the blood and controls the rise of blood glucose level after a meal.

Contraindication for Acarbose:

  • Known allergy to acarbose
  • Diabetic ketoacidosis
  • Severe liver disease
  • Intestinal conditions like inflammatory bowel disease
  • Severe kidney disease

Warning & Precautions for Acarbose:

  • Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
  • During pregnancy & Breast feeding, this medication should be used with caution. Discuss the risks and benefits with your doctor.
  • Limit alcohol consumption while taking this medication because it can increase your risk of developing low blood sugar.

Adverse Reaction/Side Effect of Acarbose:

More Common Side Effect of Acarbose is Abdominal Pain, Stomach Discomfort, Flatulence & Diarrhea.

Dosage of Acarbose:

  • Type 2 diabetes in a dose of 25 to 100 mg three times a day.
  • Tablet to take by mouth, just before the first bite of each meal.

Trade Names/Brand Names of Acarbose:

India: 

Acarex (50 mg) | Hebose | Glucar (25mg) | Zebose | K -Carb (50 mg) | Recarb | Acarb ( 25mg) | Disorb (50 mg) | Glucobay (50mg) | Olcarbos (50 mg) | Acarb ( 50mg) | Disorb | Glucar (50mg) | Gludase | Discarb | Acraz | Glucobay (25mg) | Olcarbos | Diabose (50mg) | Acarwin | Discarb (50 mg) | Acarex ( 50mg) | Glucar (25 mg) | Glubose (50 mg) | Glucarb | Asucrose (50mg) | Glucar (50mg) |

International :

Prandase, Precose, Exforge

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