ACECLOFENAC – Drug Information

Generic Name: Aceclofenac

Chemical Formula: C16H13Cl2NO4

Therapeutic Classification: None Steroidal Anti-inflamatory Drug (NSID)

Drug information about Aceclofenac. Learn its indications, dosage, how to take, when to take, when not to take, side effects, special precautions, its storage instructions and warnings if any when taken during pregnancy. Also listed are the International and Indian trade name of the drug and its price list. In 1991, aceclofenac was developed as an analog of a commonly prescribed NSAID, Diclofenac, via chemical modification in effort to improve the gastrointestinal tolerability of the drug.

Description: 

Aceclofenac is a nonsteroidal anti-inflammatory drug (NSAID) with marked anti-inflammatory and analgesic properties. It is used for the relief of pain and inflammation in rheumatoid arthritis, osteoarthritis and ankylosing spondylitis.

Mechanism of Action:

Aceclofenac works by inhibiting the action of cyclooxygenase (COX) that is involved in the production of prostaglandins (PG) which may cause pain, swelling, inflammation and fever.

Pharmacokinetics: 

It administerd by orally and the main route of elimination is via the urine where the elimination accounts for 70-80% of clearance of the drug. The mean plasma elimination half-life is approximately 4 hours

Dose:

100mg Twice Daily for Adult, take with Food or immediately after meal.

Adverse Reaction / Side Effect of Aceclofenac:

Nausea, Vomiting, Diarrhea, Constipation, Headache, Indigestion, Heartburn, Abdominal Pain, Feeling Sick, Dizziness and Skin Rash.

Pregnancy:

Aceclofenac should be avoided near term in a pregnant woman, because of the risk of having a patent ductus arteriosus in the neonate.

Warning & Precautions for Aceclofenac:

  • It should not be given to people with porphyria or breast-feeding mothers.
  • It should be avoied for the people who have history of  Peptic Ulcer, Liver and Kidney Disease.
  • It may cause dizziness or drowsiness, do not drive a car or operate machinery while taking this medication.
  • It is not be recomended for Children.
  • Should not take excess dosage.
  • It should be taken with Food or immediately after meal.

Brand Name / Trade Name:

India: 

| Acerock SR 200 | Zix | Acenal | Alnase 100 | Acebloc P | Movon-CR (400mg)| Altraflam SR (200mg) | Cycloplus | Seracemol | Cytoflam -P | Carnil AC | Zerodol-TH (8mg/100mg) (8mg/100mg) | Shinnac-SP (100mg/500mg/15mg) | Naplonac – SR | Corfen Plus A |Eclonac -P | Doloral-P (100mg/325mg) | Acepara | Elefenac Plus (100mg/500mg) | Zix -SR | Movexx Plus | Toroxx A | Vetory (200mg) | ACF Plus | Aciz SP | Viknac-S | Dibid (325mg/100mg/15mg) |

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